Hori Lab. Faculty of Science, Kyushu University

By devising and applying chemical principles, we are developing chemical biology techniques to label and visualize proteins with synthetic fluorescent molecules.

In living cells, countless biomolecules exist, dynamically changing their localization and controlling cellular events by performing the biomolecular functions in a subcellular region where they are needed. Visualization of the movement of these biomolecules provides important information to elucidate the physiological functions they control.

We have developed original technology for fluorescent labeling of proteins to reveal how proteins move in living cells and regulate biological phenomena. Furthermore, we aim to elucidate biological phenomena regulated by nucleic acids, glycans, and extracellular vesicles in addition to proteins, and to control functions of biomolecules at will by making full use of our protein labeling technology.